Monograph Details
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Cardiovascular System
> Angina
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NITROLINGUAL |
| Manufacturer |
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Sciele Pharma, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Nitrate. |
| Generic Name |
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Nitroglycerin 0.4mg/spray; lingual pump spray. |
| Indications |
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Acute attacks and prophylaxis of angina. |
| Children |
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Not recommended. |
| Adults |
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1–2 sprays at onset of attack, onto or under tongue while sitting; max 3 sprays/15 minutes. May use prophylactically 5–10 minutes before exertion. Do not inhale spray. Do not rinse mouth for 5–10 minutes after use. |
| Contraindications |
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Concomitant sildenafil. |
| Precautions |
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Acute or recent MI. Hypotension. Monitor for tolerance. Hypertrophic cardiomyopathy. Avoid abrupt cessation. Volume depletion. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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See Contraindications. Hypotension potentiated with sildenafil, alcohol, vasodilators, calcium channel blockers, other vasoactive drugs. Do not use epinephrine to treat hypotension from nitrate overdose. |
| Adverse Reactions |
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Headache, dizziness, flushing, orthostatic hypotension, paresthesia, tachycardia, nausea, rash. |
| How Supplied |
Spray—12g (200 metered sprays)
4.9g (60 metered sprays) |
| Additional Resources |
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• Related Prescribing Note |
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