Monograph Details
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Cardiovascular System
> Angina
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NITRO-DUR |
| Manufacturer |
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Schering Corporation |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Nitrate. |
| Generic Name |
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Nitroglycerin 0.1mg/hr, 0.2mg/hr, 0.3mg/hr, 0.4mg/hr, 0.6mg/hr, 0.8mg/hr; transdermal patches. |
| Indications |
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Prophylaxis of angina. Not for acute attacks. |
| Children |
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Not recommended. |
| Adults |
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Initially one 0.2–0.4mg/hr patch for 12–14hr/day. Remove patch for 10–12hrs/day. |
| Contraindications |
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Concomitant sildenafil. |
| Precautions |
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Acute or recent MI. Volume depletion. Hypotension. Heart failure. Hypertrophic cardiomyopathy. Reduce dose if hypotension occurs. Remove before defibrillation or cardioversion. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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See Contraindications. Severe hypotension with sildenafil. Hypotension potentiated with alcohol, other vasodilators, calcium channel blockers. |
| Adverse Reactions |
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Headache, increased angina, dizziness, flushing, orthostatic hypotension, tachycardia, nausea, rash. |
| How Supplied |
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Patch—30 |
| Additional Resources |
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• Related Prescribing Note |
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