Monograph Details
|
|
Cardiovascular System
> Angina
|
|
MINITRAN |
| Manufacturer |
|
Graceway Pharmaceuticals |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Nitrate. |
| Generic Name |
|
Nitroglycerin 0.1mg/hr, 0.2mg/hr, 0.4mg/hr, 0.6mg/hr; transdermal patches. |
| Indications |
|
Prophylaxis of angina. Not for acute attacks. |
| Children |
|
Not recommended. |
| Adults |
|
Initially one 0.2mg/hr or 0.4mg/hr patch for 12–14hrs/day. Remove patch for 10–12hrs/day. |
| Contraindications |
|
Concomitant sildenafil. |
| Precautions |
|
Acute or recent MI. Volume depletion. Hypotension. Heart failure. Hypertrophic cardiomyopathy. Reduce dose or discontinue if hypotension occurs. Remove before defibrillation or cardioversion. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
|
See Contraindications. Severe hypotension with sildenafil. Hypotension potentiated with alcohol, other vasodilators, calcium channel blockers. |
| Adverse Reactions |
|
Headache, dizziness, flushing, hypotension, increased angina, tachycardia, faintness, nausea, vomiting, rash. |
| How Supplied |
|
Patch—30 |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
