Monograph Details

Cardiovascular System > Angina
ISMO
Manufacturer
PDL BioPharma, Inc.
Legal Classification
Rx
Pharmacological Class
Nitrate.
Generic Name
Isosorbide mononitrate 20mg; scored tabs.
Indications
Prophylaxis of angina. Not for acute attacks.
Children
Not recommended.
Adults
20mg upon awakening then 20mg 7 hrs later.
Contraindications
Concomitant sildenafil.
Precautions
Acute MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Monitor for tolerance. Pregnancy (Cat.C). Nursing mothers.
Interactions
See Contraindications. Severe hypotension with sildenafil. Orthostatic hypotension with alcohol, calcium channel blockers.
Adverse Reactions
Headache, dizziness, orthostatic hypotension, bradycardia, GI upset, syncope.
How Supplied
Tabs—100
Additional Resources
Related Prescribing Note