Monograph Details
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Cardiovascular System
> Angina
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IMDUR |
| Manufacturer |
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Schering Corporation |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Nitrate. |
| Generic Name |
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Isosorbide mononitrate 30mg+, 60mg+, 120mg; ext rel tabs; +scored. |
| Indications |
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Prevention of angina. Not for acute attacks. |
| Children |
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Not recommended. |
| Adults |
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Do not crush or chew. Take with fluid. Initially 30–60mg once daily in the AM. May increase to 120mg once daily; usual max 240mg once daily. |
| Contraindications |
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Concomitant sildenafil. |
| Precautions |
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Acute MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Monitor for tolerance. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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See Contraindications. Severe hypotension with sildenafil. Orthostatic hypotension with alcohol, calcium channel blockers. |
| Adverse Reactions |
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Headache, dizziness, hypotension. |
| How Supplied |
Tabs 30mg––30, 100
60mg, 100mg—100 |
| Additional Resources |
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• Related Prescribing Note |
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