Monograph Details
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Allergic Disorders
> Anaphylaxis
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EPIPEN |
| Manufacturer |
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DEY Pharma |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Sympathomimetic. |
| Generic Name |
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Epinephrine 0.3mg (1:1000); auto-injection device; contains sulfites. |
| Also |
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• EPIPEN Jr
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| Indications |
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Emergency treatment in anaphylaxis. |
| Children |
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0.01mg/kg IM in thigh; may repeat if needed. |
| Adults |
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0.3mg IM in thigh; may repeat if needed. |
| Precautions |
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Cardiovascular disease. Hypertension. Hyperthyroidism. Diabetes. Advise patient to seek medical help immediately. Train patient in use of device. Elderly. Children. Pregnancy (Cat.C). |
| Interactions |
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Pressor effects may be potentiated by MAOIs, tricyclic antidepressants, furazolidone, antihistamines, levothyroxine, β-blockers, guanethidine. May be antagonized by nitrites, α-blockers, other rapid-acting vasodilators. Arrhythmias possible with digitalis, mercurial diuretics, quinidine, others. |
| Adverse Reactions |
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Tachycardia, sweating, nausea, vomiting, respiratory difficulty, pallor, dizziness, weakness, tremor, headache, nervousness, anxiety, arrhythmia. |
| How Supplied |
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Both—1, 2 |
| Additional Resources |
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• Related Prescribing Note |
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