Monograph Details
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Allergic Disorders
> Anaphylaxis
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ADRENALIN |
| Manufacturer |
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JHP Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Sympathomimetic. |
| Generic Name |
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Epinephrine (as HCl) 1mg/mL; inj; contains sulfites. |
| Indications |
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Emergency treatment in anaphylaxis. Bronchospasm. Urticaria. Angioedema. Serum sickness. |
| Children |
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0.01mg/kg (max 0.5mg) SC every 4 hrs as needed. |
| Adults |
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0.2–1mg SC (preferred) or IM (avoid buttocks) every 4 hrs as needed. |
| Contraindications |
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Narrow angle glaucoma. Cardiac failure. Shock. Organic brain damage. Cardiac dilatation. Coronary insufficiency. General anesthesia with cyclopropane or halogenated hydrocarbons. Local anesthesia of fingers, toes. Labor. |
| Precautions |
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Cardiovascular disease. Hypertension. Diabetes. Hyperthyroidism. Psychoneurosis. Elderly. Pregnancy (Cat.C). |
| Interactions |
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Pressor effects may be potentiated by tricyclic antidepressants, antihistamines, levothyroxine, β-blockers, guanethidine. May be antagonized by nitrites, α-blockers. Avoid digitalis and other arrhythmia-producing agents. |
| Adverse Reactions |
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Anxiety, headache, fear, palpitations, local necrosis, pulmonary edema, hypertension, cerebral hemorrhage. |
| How Supplied |
Single-dose vial (1mL)—25
Multi-dose vial (30mL)—1 |
| Additional Resources |
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• Related Prescribing Note |
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