Monograph Details
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Allergic Disorders
> Allergies
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XYZAL ORAL SOLUTION |
| Manufacturer |
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UCB and Sanofi Aventis |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antihistamine. |
| Generic Name |
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Levocetirizine dihydrochloride 0.5mg/mL. |
| Also |
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• XYZAL
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| Indications |
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Allergic rhinitis (seasonal and perennial). Chronic idiopathic urticaria. |
| Children |
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<6yrs: not recommended. 6–11yrs: max 2.5mg once daily in the PM. Renal dysfunction: contraindicated. |
| Adults |
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2.5mg–5mg once daily in the PM. Renal dysfunction: CrCl 50–80mL/min: 2.5mg once daily; CrCl 30–50mL/min: 2.5mg every other day; CrCl 10–30mL/min: 2.5mg twice per week (every 3–4 days); CrCl <10 mL/min or hemodialysis: contraindicated. |
| Contraindications |
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End-stage renal disease (CrCl <10mL/min) or hemodialysis (>12yrs of age). Impaired renal function (<12yrs of age). |
| Precautions |
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Do not exceed recommended dose. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Avoid alcohol, other CNS depressants. May be potentiated by theophylline. Potentiated by ritonavir. |
| Adverse Reactions |
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Adults: somnolence, nasopharyngitis/pharyngitis, fatigue, dry mouth. Children: pyrexia, somnolence, cough, epistaxis. |
| How Supplied |
Tabs—90
Soln—150mL |
| Additional Resources |
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• Related Prescribing Note |
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