Monograph Details
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Allergic Disorders
> Allergies
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SINGULAIR ORAL GRANULES |
| Manufacturer |
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Merck & Co., Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Leukotriene receptor antagonist. |
| Generic Name |
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Montelukast (as sodium) 4mg; per packet. |
| Also |
• SINGULAIR
• SINGULAIR CHEWABLE
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| Indications |
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Seasonal allergic rhinitis (for patients ≥2 years old). Perennial allergic rhinitis (for patients ≥6 months old). |
| Adults and Children |
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Take granules by mouth within 15 minutes of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <6months: not recommended. 6–23months: one 4mg granule packet. 2–5yrs: one 4mg chew tab or granule packet. 6–14yrs: one 5mg chew tab. ≥15yrs: one 10mg tab. For all: take once daily. |
| Precautions |
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Caution when withdrawing from oral steroids. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Monitor with potent CYP450 inducers (eg, phenobarbital, rifampin). Caution with drugs metabolized by CYP2C8 (eg, paclitaxel, rosiglitazone, repaglinide). |
| Adverse Reactions |
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Adults: upper respiratory infection. Children: also headache, otitis media, pharyngitis. |
| How Supplied |
Tabs, chew tabs—30, 90
Oral granules—30 |
| Additional Resources |
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• Related Prescribing Note |
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