Monograph Details

Allergic Disorders > Allergies
Cyproheptadine
Manufacturer
Various generic manufacturers
Legal Classification
Rx
Pharmacological Class
Antihistamine.
Generic Name
Cyproheptadine HCl 4mg; scored tabs.
Indications
Allergic and vasomotor rhinitis, conjunctivitis, urticaria, angioedema, reactions to blood. Adjunct in anaphylaxis. Cold urticaria. Dermatographism.
Children
<2yrs: not recommended. 2–6yrs: 2mg 2–3 times per day; max 12mg daily. 7–14yrs: 4mg 2–3 times per day; max 16mg daily.
Adults
≥14yrs: initially 4mg 3 times daily; usual range 12–16mg/day; max 0.5mg/kg per day.
Contraindications
MAOIs. Glaucoma. GI or urinary obstruction. Elderly. Debilitated. Neonates. Premature infants. Nursing mothers.
Precautions
Hyperthyroidism. Cardiovascular disease. Hypertension. Increased intraocular pressure. History of asthma. Pregnancy (Cat.B).
Interactions
See Contraindications. Anticholinergic effects potentiated by MAOIs. Potentiates CNS depression with alcohol, other CNS depressants.
Adverse Reactions
Drowsiness, dizziness, paradoxical excitement, anticholinergic effects, gastritis, hypotension, blood dyscrasias.
How Supplied
Contact supplier.
Additional Resources
Related Prescribing Note